[Full Picture] 2,4-Dichlorophenol Increases Primordial Germ Cell Numbers via ESR2a-Dependent Pathway in Zebrafish Larvae

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Source: pubmed.ncbi.nlm.nih.gov

May be slightly imbalanced

Summary Analysis Research

1. 2,4-DCP暴露可以增加初级生殖细胞（PGC）数量，导致雌性偏向的性别分化。

2. 2,4-DCP与zebrafish ESR2a结合，通过ESR2a信号通路介导PGC数量的增加。

3. 2,4-DCP刺激vasa和dnd启动子活性是通过雌激素反应元件（ERE）介导的。

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